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Usage in PregnancyThe safety of Mestinonpyridostigmineduring pregnancy or lactation in humans has not been establishedThereforeuse of Mestinonpyridostigminein women who may become pregnant requires weighing the drug’s potential benefits against its possible hazards to mother and child.

For detailed information on the management of patients with myasthenia gravisthe physician is referred to one of the excellent reviews such as those by Osserman and Genkins2 Grob 3 or Schwab4,5.

Mestinon is a cholinesterase inhibitor that reversibly inhibits the esterase enzyme that is responsible for breaking down acetylcholinea neurotransmitter that transmits nerve signals to the musclesresulting in increased levels as well as duration of the acetylcholine activity.

NOTEFor information on a diagnostic test for myasthenia gravisand for the evaluation and stabilization of therapyplease see product literature on Tensilonedrophonium chloride

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in a controlled study of 90 healthy volunteers comparing mestinon-sr 30 mg every 8 hours to placebo for 21 days, the following incidence of adverse reactions was reported.