Metformin preferentially inhibits nuclear translocation of nf-kb and phosphorylation of stat3 in cancer stem cells compared with non-stem cancer cells in the same population.
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However it’sthe medication I was onwell put on was metformin and gliclazide I think it’s calledand it’s taken all of six months to get it under control and it’s been that way now for the last four weeksand it’ll range somewhere between 3.5 and 7 on a daily basisI still take the odd thing that I shouldn’t take likepiece of chocolatealthough I eliminated sweets as such and sugar in tea and coffeeI think I found through experience that it’s not doing without it’sbeing reasonable with thingsExcept alcoholand that’s just not onI don’t have a problem with itI don’t have a problem on the medicationa few pills during the course of the day is not much to ask to keep your health in checkSo overall I suppose I’ve been fairly luckyand perhaps I’ve not had the stage of crisis yet I don’t know butI hope to avoid that.
If you’ve taken too many metformin tablets go to your nearest hospital accident and emergencyA&Edepartment straight away.
It’s a good idea to cut down on foods with added sugarCheck the nutrition labels as many foods and drinks are high in sugarsuch as:
Sulphonylureas such as gliclazide pioglitazone DPP-4 inhibitors such as saxagliptin SGLT2 inhibitors such as dapagliflozin GLP-1 agonists such as exenatide insulin.
Type 2 diabetes is an illness where the body doesn’t make enough insulinor the insulin that it makes doesn’t work properlyThis can cause high blood sugar levelshyperglycemia
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food and drug administration fda to exercise caution in prescribing metformin to individuals with chronic kidney disease ckd , unstable congestive heart failure chf , chronic liver disease cld , and older age due to perceived risk of side effects, including lactic acidosis la .
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