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Information about Chloramphenicol.

Chloramphenicol injection is used to treat certain types of serious infections caused by bacteria when other antibiotics cannot be usedChloramphenicol injection is in a class of medications called antibioticsIt works by stopping the growth of bacteria

From the solubility curves two different blends were selected so as to incorporate 4 mg/ml and 5 mg/ml drug in the blend in the solubilized formThese were formulated into two different solution dosage forms MVA1 and MVA2The two formulations were prepared in bulksterile filtered using a G5 filter under aseptic conditionsThey were transferred into sterile glass vials under aseptic conditionsSterile rubber closures saturated with benzalkonium chloride were used in closing the vialsThe vials were both amber coloured and plain vials because chloramphenicol is light sensitive and plain coloured vials were used to test the stability under accelerated light conditionsThe various parameters of the formulations were vizviscositycolourclaritypH and drug concentration.

Chloramphenicol does not provide coverage against Pseudomonas sppor serratia marcescens.

Wash your hands before you use the ointmentRemove the cap from the tubeTilt your head back a little and pull the lower lid of your eye downwards to form a pocketHold the tube upside down near to your eyeApply enough pressure to the tube to release a thin line of ointment along the inside of the lower eyelidTry not to touch your eye as you do thisClose your eye for a moment or twoand then blink a few times to spread the ointment around the inside of your eyeRepeat the process in your other eye if both eyes are affectedWhen you have finishedremember to replace the cap on the tube to prevent the ointment from becoming contaminated.

Use chloramphenicol eye ointment 3-4 times dailyAlternativelyif you are using chloramphenicol eye drops during the dayuse the ointment once at bedtime.

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in addition to being a useful target, chloramphenicol was chosen as during previous rounds of synthesis-golf, several people commented that they d like to see targets amenable to biosynthetic transformations, and scaleable process routes.