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Cephalosporins may be associated with prolonged prothrombin timeThose at risk include patients with renal or hepatic impairmentor poor nutritional stateas well as patients receiving a protracted course of antibacterial therapyand patients receiving anticoagulant therapyMonitor prothrombin time in patients at risk and manage as indicated.
Monitoring HematologicProthrombin timeespecially in patients at risk of prolonged prothrombin timeRenalRenal functionespecially in patients with renal dysfunction)
Prescribing KEFLEX in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Cephalexin may reduce the effect of BCG and typhoid vaccinesCephalexin should not be combined with BCG or typhoid vaccine unless there are no other options.
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