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This appears to be the only clinically relevant interaction of this kind with Lariammefloquinealthough theoreticallycoadministration of other drugs known to alter cardiac conductioneganti-arrhythmic or beta-adrenergic blocking agentscalcium channel blockersantihistamines or H 1blocking agentstricyclic antidepressants and phenothiazinesmight also contribute to a prolongation of the QTc intervalThere are no data that conclusively establish whether the concomitant administration of mefloquine and the above listed agents has an effect on cardiac function.
Malaria is an infection that can cause death and is spread to humans through mosquito bitesIf you travel to parts of the world where the mosquitoes carry the malaria parasiteyou must take a malaria prevention medicineLariammefloquineis one of a small number of medications approved to prevent and to treat malariaIf taken correctlyLariammefloquineis effective at preventing malaria butlike all medicationsit may produce side effects in some patients.
Among subjects who received mefloquine for treatmentthe most frequently observed adverse experiences includeddizzinessmyalgianauseafeverheadachevomitingchillsdiarrheaskin rashabdominal painfatigueloss of appetiteand tinnitusThose side effects occurring in less than 1included bradycardiahair lossemotional problemspruritusastheniatransient emotional disturbances and telogen effluviumloss of resting hairSeizures have also been reported.
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