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The methods recommended for early diagnosis ofchloroquine retinopathyconsist of1funduscopic examination of the macula for fine pigmentary disturbances or loss of the foveal reflex and2examination of the central visual field with a small red test object for pericentral or paracentral scotoma or determination of retinal thresholds to redAny unexplained visual symptomssuch as light flashes or streaksshould also be regarded with suspicion as possible manifestations of retinopathy.
Skeletal muscle palsies or skeletal muscle myopathy or neuromyopathy leading to progressive weakness and atrophy of proximal muscle groups which may be associated with mild sensory changesdepression of tendon reflexes and abnormal nerve conduction.
Heart diseaseRarelyweakening of the heart muscle has been reported with the use of hydroxychloroquineIf you have heart diseasediscuss with your doctor how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.
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