Do not use this medication if you are allergic to enalapril or to any other ace inhibitor, such as benazepril lotensin , captopril capoten , fosinopril monopril , lisinopril prinivil, zestril , moexipril univasc , perindopril aceon , quinapril accupril , ramipril altace , or trandolapril mavik .
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Anaphylactoid Reactions during LDL ApheresisRarelypatients receiving ACE inhibitors during low density lipoproteinLDLapheresis with dextran sulfate have experienced life-threatening anaphylactoid reactionsThese reactions were avoided by temporarily withholding ACE inhibitor therapy prior to each apheresis.
A symptom complex has been reported which may include fevervasculitismyalgiaarthralgia/arthritisa positive ANAelevated ESReosinophilia and leukocytosisRashphotosensitivity or other dermatologic manifestations may also occur.
Liver problemsnauseaupper stomach painitchingtired feelingloss of appetitedark urineclay-colored stoolsjaundiceyellowing of the skin or eyes
Angiotensin converting enzymeACEis a peptidyl dipeptidase which catalyzes the conversion of angiotensin I to the pressor substanceangiotensin IIInhibition of ACE results in decreased plasma angiotensin IIwhich leads to increased plasma renin activitydue to removal of negative feedback of renin releaseand decreased aldosterone secretionAlthough the latter decrease is smallit results in a small increase in serum KIn patients treated with lisinopril and a thiazide diuretic there was essentially no change in serum potassiumsee Precautions
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a although furosemide lasix and lisinopril prinivil, zestril may interact to more powerfully lower blood pressure, their use together is possible with special precautions, such as careful monitoring and dosage adjustment.
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