Colchicine gout over the counter

You must take colchicine exactly as your doctor tells you to.

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Taking certain medicines with colchicine capsules can cause your level of colchicine to be too highespecially if you have kidney or liver problemsTell your healthcare provider about all your medical conditionsincluding if you have kidney or liver problemsYour dose of colchicine capsules may need to be changedEven medicines that you take for a short period of timesuch as antibioticscan interact with colchicine capsules and cause serious side effects or death.

Patients with renal or hepatic impairment should not be given colchicine capsules with drugs that inhibit both P-glycoprotein and CYP3A4 inhibitorsSee DRUG INTERACTIONSCombining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity.

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After completion of a courseanother course should not be started for at least 3 days72 hours

Colchicine is used to prevent gout attackssuddensevere pain in one or more joints caused by abnormally high levels of a substance called uric acid in the bloodin adultsand to relieve the pain of gout attacks when they occurColchicine is also used to treat familial Mediterranean feverFMFan inborn condition that causes episodes of feverpainand swelling of the stomach arealungsand jointsin adults and children 4 years of age and olderColchicine is not a pain reliever and cannot be used to treat pain that is not caused by gout or FMFColchicine is in a class of medications called anti-gout agentsIt works by stopping the natural processes that cause swelling and other symptoms of gout and FMF.

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the limited information regarding in vivo human colchicine metabolism could be partially due to low quantities of radiolabeled samples available from patients as therapeutic doses of colchicine are low cerquaglia et al.