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Cases of JC virus-associated infection resulting in progressive multifocal leukoencephalopathyPMLsometimes fatalhave been reported in patients treated with immunosuppressantsincluding ImuranRisk factors for PML include treatment with immunosuppressant therapies and impairment of immune functionConsider the diagnosis of PML in any patient presenting with new-onset neurological manifestations and consider consultation with a neurologist as clinically indicatedConsider reducing the amount of immunosuppression in patients who develop PMLIn transplant patientsconsider the risk that the reduced immunosuppression represents to the graft.
If you forget to take a dose of Imurantake it as soon as you remember and then continue to follow your regular dosing schedule.
There are potential hazards in the use of ImuranIt should be prescribed only if the patient can be adequately monitored for toxic effects throughout the duration of therapy.
IMURAN can cause fetal harm when administered to a pregnant womanIMURAN should not be given during pregnancy without careful weighing of risk versus benefitWhenever possibleuse of IMURAN in pregnant patients should be avoidedThis drug should not be used for treating rheumatoid arthritis in pregnant women12.
Some mild nausea often occurs when you start taking ImuranThis discomfort is expected and will go away as your body gets used to the medicationIf you have extreme nausea with vomitingcontact your doctorWhile you are taking this medicationyou may be asked to have regular blood testssuch as blood cell counts and liver function teststo evaluate the medication’s effectiveness and to monitor your response to the drugKeep all appointments with your doctor and the labYour doctor may reduce or even stop Imuran when you are being treated for certain infectionsThis allows your body to effectively fight backBe sure that you always have enough medication on handCheck your supply before holidays or other occasions when you may be unable to fill your prescriptionDo not have any vaccinations without your doctor’s approvalTake precautions to avoid infection while taking this drugAvoid anyone who may have an infection and report any signs of infection to your doctor.
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imuran may be associated with a dose-related, generally reversible, depression of bone marrow function, most frequently expressed as leucopenia, but also sometimes as anaemia and thrombocytopenia, and rarely as agranulocytosis, pancytopenia and aplastic anaemia.
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