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Hydroxyurea may cause a drop in platelet countsan important type of blood cells required for forming blood clotsUse of hydroxyurea with anticoagulantsnonsteroidal anti-inflammatory drugsNSAIDsantiplateletsand thrombolytic agents increases the risk of bleeding.
Hydroxyurea may be used as part of a combination therapyThis means you may need to take it with other medications.
Hydroxyurea can irritate or damage your skin if the medication comes in contact with your skinWash your hands before and after handling the capsules or the bottle.
Hydroxyurea may cause other cancerssuch as secondary leukemiaskin cancerProtect your skin from the sunAvoid prolonged sun exposuretanning boothsand sunlampsUse sunscreen and wear protective clothing when outdoorsTell your doctor right away if you notice any symptoms of cancersuch as swollen glandssudden weight lossnight sweatsor unusual skin growths/moles.
Following oral administration of HYDREAhydroxyurea reaches peak plasma concentrations in 1 to 4 hoursMean peak plasma concentrations and AUCs increase more than proportionally with increase of dose.
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