The cdc also recommends isoniazid 15 mg kg rounded to the nearest 50 or 100 mg; max 900 mg po in combination with rifapentine once weekly for 12 weeks under directly observed therapy dot , which is equal to the 9-month daily isoniazid regimen.

Information about Isoniazid.
The risk of peripheral neuropathy is excluded if vulnerable patients receive daily supplements of pyridoxineOther less common forms of neurological disturbanceincluding optic neuritistoxic psychosis and generalized convulsionscan develop in susceptible individualsparticularly in the later stages of treatmentand occasionally necessitate the withdrawal of isoniazid.
AntacidsAluminum salts will decrease the action of isoniazidDo not take antacids that contain aluminum for 1 to 2 full hours before or after taking a dose of isoniazidketoconazoleNizoraland itraconazoleSporanoxIsoniazid may decrease the actions of these antifungal medicinesThereforea fungal infection may not be adequately treatedrifampinRimactaneRifadinor rifabutinMycobutindisulfiramAntabuseUnusual behavior and coordination difficulties may occur if these medicines are taken together.
How does isoniazid workIsoniazid prevents bacteria from manufacturing certain components needed for the formation of bacterial cell wallsWithout a cell wall the bacteria will die.
This product may cause live bacterial vaccinessuch as BCG vaccineto not work as wellThereforedo not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
Isoniazid comes as a tablet and a solutionliquidto take by mouth without foodIsoniazid is usually is taken once a dayit may also be taken onetwoor three times weeklyTake isoniazid at around the same time every scheduled dayFollow the directions on your prescription label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake isoniazid exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor.
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patients should be counseled to avoid ethanol-containing beverages while taking isoniazid.
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