Nano-lipoidal carriers such as solid lipid nanoparticles and nanostructured lipidic carriers have been shown to enhance the photostability and skin delivery of tretinoin.

Information about Tretinoin.
Use only nonmedicated cosmetics on cleansed skinDo not use topical preparations with a lot of alcoholmentholspicesor limee.gshaving lotionsastringentsand perfumesthey can sting your skinespecially when you first use tretinoin.
Minimize exposure to the sun and to extreme cold or windAvoid sunlampstanning beds and ultraviolet lightuse a sunscreen with a SPF of at least 15wear protective clothing and wide-brimmed hat stop using tretinoin if you get a sunburn avoid washing your skin too oftenscrubbing the affected skinor using other products with a drying effectincluding other products containing tretinoinunless recommended by your healthcare provider.
Weather extremessuch as wind or coldalso may be irritating to patients under treatment with tretinoinRETIN-Atretinoinacne treatment should be kept away from the eyesthe mouthangles of the noseand mucous membranesTopical use may induce severe local erythema and peeling at the site of applicationIf the degree of local irritation warrantspatients should be directed to use the medication less frequentlydiscontinue use temporarilyor discontinue use altogetherTretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition.
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exposure to sunlight, including sunlamps, should be minimized during the use of tretinoin, and patients with sunburn should be advised not to use the product until fully recovered because of heightened susceptibility to sunlight as a result of the use of tretinoin.
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