In rheumatoid arthritis, age at first use of methotrexate and duration of therapy have been reported as risk factors for hepatotoxicity; other risk factors, similar to those observed in psoriasis, may be present in rheumatoid arthritis but have not been confirmed to date.

Information about Methotrexate.
Temporary hair loss may occurNormal hair growth should return after treatment has ended.
Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have low blood cell countsa bone marrow disorderliver diseaseespecially if caused by alcoholismor if you are pregnant or breast-feeding.
Examples of drugs that can cause interactions with methotrexate are listed below.
Call your doctor if you have unusual bruising or bleedingor signs of infectionfeverchillsbody aches
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