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Dexamethasone is used to treat conditions such as arthritisblood/hormone/immune system disordersallergic reactionscertain skin and eye conditionsbreathing problemscertain bowel disordersand certain cancersIt is also used as a test for an adrenal gland disorderCushing’s syndrome
Do not stop taking this medication without consulting your doctorSome conditions may become worse when this drug is suddenly stoppedYour dose may need to be gradually decreased.
How is dexamethasone typically givenadministeredDexamethasone may be administered in several different waysorally as an elixir or tabletsintravenouslyinto a veinintramuscularlyinto a muscleintralesionlyinto a lesioninto soft tissueintraarticularlyinto the cavity of a jointas eye dropsor as a lotionThe dose depends on several factorsincluding the condition being treatedthe size of the patientthe particular regimen being used and the overall health of the patient.
Corticosteroids have been shown to be teratogenic in many species when given in doses equivalent to the human doseAnimal studies in which corticosteroids have been given to pregnant miceratsand rabbits have yielded an increased incidence of cleft palate in the offspringThere are no adequate and well-controlled studies in pregnant womenCorticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetusInfants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism.
CardiovascularBradycardiacardiac arrestcardiac arrhythmiascardiac enlargementcirculatory collapsecongestive heart failurefat embolismhypertensionhypertrophic cardiomyopathy in premature infantsmyocardial rupture following recent myocardial infarctionedemapulmonary edemasyncopetachycardiathromboembolismthrombophlebitisvasculitis.
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