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If you are taking metoclopramide to treat the symptoms of slow stomach emptying caused by diabetesyou should know that your symptoms will not improve all at onceYou may notice that your nausea improves early in your treatment and continues to improve over the next 3 weeksYour vomiting and loss of appetite may also improve early in your treatmentbut it may take longer for your feeling of fullness to go away.
Can cause tardive dyskinesiasee Black Box Warningsespecially in elderlydiscontinue if signs or symptoms of tardive dyskinesia developmetoclopramide itself may completely or partially suppress these manifestationstardive dyskinesia may persist even after drug is discontinued.
Avoid driving or hazardous activity until you know how this medicine will affect youYour reactions could be impaired.
Taking metoclopramide may cause you to develop a muscle problem called tardive dyskinesiaIf you develop tardive dyskinesiayou will move your musclesespecially the muscles in your face in unusual waysYou will not be able to control or stop these movementsTardive dyskinesia may not go away even after you stop taking metoclopramideThe longer you take metoclopramidethe greater the risk that you will develop tardive dyskinesiaThereforeyour doctor will probably tell you not to take metoclopramide for longer than 12 weeksThe risk that you will develop tardive dyskinesia is also greater if you are taking medications for mental illnessif you have diabetesor if you are elderlyespecially if you are a womanCall your doctor immediately if you develop any uncontrollable body movementsespecially lip smackingmouth puckeringchewingfrowningscowlingsticking out your tongueblinkingeye movementsor shaking arms or legs.
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pubmed 17016423 burger dm, wiestner t, hubler m, binder h, keiser m, arnold s effect of anticholinergics atropine, glycopyrrolate and prokinetics metoclopramide, cisapride on gastric motility in beagles and labrador retrievers.
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