The most serious side effect that glucovance mite can cause is called lactic acidosis.
Information about Glucovance.
Take this medication by mouth with meals as directed by your doctorusually once or twice a dayDrink plenty of fluids while taking this medication unless otherwise directed by your doctor.
Patients receiving Glucovance in combination with a thiazolidinedione may be at risk for hypoglycemia.
There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with Glucovance or any other antidiabetic drug.
The dosage is based on your medical condition and response to treatmentTo reduce your risk of side effectssuch as upset stomach and low blood sugaryour doctor may direct you to start this medication at a low dose and gradually increase your doseYour doctor will adjust your dose based on your blood sugar to find the best dose for youFollow your doctor’s instructions carefully.
There have been post-marketing cases of metformin-associated lactic acidosisincluding fatal casesThese cases had a subtle onset and were accompanied by nonspecific symptoms such as malaisemyalgiasabdominal painrespiratory distressor increased somnolencehoweverhypotension and resistant bradyarrhythmias have occurred with severe acidosisMetformin-associated lactic acidosis was characterized by elevated blood lactate concentrations5 mmol/Lanion gap acidosiswithout evidence of ketonuria or ketonemiaand an increases lactate:pyruvate ratiometformin plasma levels were generally5 mcg/mLMetformin decreases liver uptake of lactate increasing lactate blood levels which may increase the risk of lactic acidosisespecially in patients at risk.
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although there are no reports to support fetal harm caused by glucovance; doctors normally don t prescribe this medicine for pregnant women.
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